Photothermal conditioning of platelet-rich plasma: mechanisms and emerging applications in hair regeneration

AUTHORS

Ilknur Nihal Ardic, Nurittin Ardic

ABSTRACT

Photothermal conditioning of platelet-rich plasma (PRP) is an emerging innovation in regenerative medicine, particularly in the field of hair restoration. By using controlled electromagnetic energy, this technique modulates the biological activity of PRP, potentially enhancing the release of growth factor, production of exosomes and communication between cells. This review aims to explore the mechanisms behind photothermal PRP, summarize current preclinical and clinical findings, and evaluate its applications in hair regeneration. A comprehensive literature review was conducted across multiple databases to evaluate mechanistic data, clinical outcomes and technology platforms.