MCT System · Add-on

Exo-Tech

An injectable autologous matrix combining Plasma Gel with PRP enriched with the patient’s own platelet-derived exosomes.

How it worksClinical FAQs

What it does

Exo-Tech: An autologous scaffold designed to support local retention of platelet-derived extracellular vesicles.

Plasma gel alone is structural. Exo-Tech Gel adds the biological signal.

Plasma Gel scaffold

Platelet-poor plasma (PPP) thermally processed into a three-dimensional protein-based matrix that provides structural support and a framework for incorporating biological components.

MCT Exosomes

PRP photothermally biomodulated using the Exosomes preset to promote the release of platelet-derived exosomes.

Fully autologous

Both components are obtained from the patient’s own blood in a single blood draw, without the addition of synthetic polymers.

Inside Exo-Tech Gel

MCT Exosomes in a Plasma Gel scaffold

A three-dimensional protein network that incorporates MCT Exosomes, combining the structural properties of plasma gel with platelet-derived exosomes and growth factors to support their local retention.

Sustained release potential

The plasma gel acts as a local reservoir for MCT Exosomes, with the potential to support the gradual release of bioactive components over time.

Matrix-mediated protection

The three-dimensional protein network provides a supportive environment for incorporated bioactive components, potentially limiting their early dispersion and degradation.

Complementary action

Structural support from the plasma gel scaffold, combined with the biological signalling potential of MCT Exosomes.

Fully autologous

Fully autologous, without added synthetic polymers. The plasma gel is naturally biodegradable, with related heat-treated plasma formulations showing persistence for up to 3–6 months.

The system

Built on the MCT System

Exo-Tech combines two complementary technologies: the MCT System conditions PRP to obtain MCT Exosomes, while the Exo-Tech Dry Bath prepares the autologous plasma gel scaffold.

Add-on

Exo-Tech Dry Bath

A controlled heating program at 90 °C transforms platelet-poor plasma (PPP) into a viscoelastic plasma gel.

Plasma gel

Core technology

MCT System

Photothermal biomodulation with the Exosomes preset promotes the release of platelet-derived exosomes, obtaining MCT Exosomes.

MCT Exosomes

The protocol

Three steps at the point of care

One blood draw, two syringes: plasma gel prepared from PPP and MCT Exosomes obtained from PRP, combined to form Exo-Tech Gel.

Plasma gel

PPP is thermally processed in the Exo-Tech Dry Bath at 90 °C to form a viscoelastic protein-based gel, which is then cooled to 37 °C or below before mixing.

MCT Exosomes

PRP from the same blood draw undergoes photothermal conditioning using the MCT Exosomes preset.

Exo-Tech Gel

Both preparations are connected using a Luer-lock connector and mixed until homogeneous, obtaining Exo-Tech Gel ready for clinical application.

Heating time determines gel consistency

Under controlled heating conditions, exposure time influences protein structuring and determines the final consistency of the plasma gel.

  • 3 minSoft More fluid consistency, allowing easier spreading.
  • 6 minIntermediate Balanced consistency between fluidity and structural support.
  • 9 minFirm Greater firmness and cohesiveness for increased structural support.

Scientific background

Scientific foundations of Exo-Tech

Published research on MCT Exosomes, autologous plasma gel and hydrogel-based exosome delivery provides the scientific rationale behind Exo-Tech. These publications investigate the individual components and related technologies, rather than the combined Exo-Tech Gel preparation.

All MCT publicationsWatch the webinars

Autologous platelet-rich plasma exosome quantification after two thermo-photobiomodulation protocols with different fluences

Journal of Photochemistry and Photobiology · 2025 — Laura Cordero, Joan Carles Domingo, Elena Sánchez-Vizcaíno Mengual, Hernán Pinto

MCT Exosomes research

Assessment of the efficacy and safety of platelet poor plasma gel as autologous dermal filler for facial rejuvenation

Journal of Cosmetic Dermatology · 2019 — Doghaim NN, El-Tatawy RA, Neinaa YME

Autologous Plasma Gel research

Platelet-poor plasma gel vs platelet-rich plasma for infraorbital rejuvenation: a clinical and dermoscopic comparative study

Dermatologic Therapy · 2020 — Neinaa YME, Hodeib AAE, Morquos MM, Elgarhy LH

Autologous Plasma Gel research

In vivo assessment of plasma gel: regenerative potential and limitations as a filler

Journal of Cosmetic Dermatology · 2025 — Cheng H, Li J, Zhao Y, Xia X, Li Y

Autologous Plasma Gel research

Hydrogel-exosome system in tissue engineering: a promising therapeutic strategy

Bioactive Materials · 2024 — Fan MH, Pi JK, Zou CY, et al.

Hydrogel-based exosome delivery

Hydrogels for exosome delivery in biomedical applications

Gels · 2022 — Xie Y, Guan Q, Guo J, Chen Y, Yin Y, Han X

Hydrogel-based exosome delivery

Clinical FAQs

A 15-page guide for clinicians

Preparation, density selection, injection technique and safety. Request it with the form below; some of the questions it answers:

  1. How does Exo-Tech Gel differ from plasma gel alone?
  2. Do the 3-, 6- and 9-minute values represent concentration?
  3. How should plasma gel density be selected?
  4. Is there a risk of vascular occlusion, and how is it managed?
  5. Can Exo-Tech Gel be combined with HA fillers in the same session?

Exo-Tech in Practice: Answers to the Most Common Clinical Questions

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