MCT System · Preset

MCT Exosomes

Photothermal biomodulation to obtain autologous PRP enriched with platelet-derived exosomes.

Blue light
Controlled temperature (37 °C)

Platelet-derived exosome release
EV-enriched PRP

Autologous
Prepared at the point of care

What it does

Photothermal biomodulation stimulates the release of platelet-derived exosomes, enriching the patient’s own PRP.

Bioactive PRP composition

The resulting preparation retains the naturally occurring components of PRP, including platelets and growth factors, alongside the released extracellular vesicles.

Autologous PRP enriched with platelet-derived exosomes

Platelet-derived exosomes remain within the patient’s own PRP, without requiring a separate exosome isolation step.

Clinical applications

The clinical potential of MCT Exosomes has been explored across different therapeutic areas, including aesthetic medicine, dermatology, musculoskeletal care and wound management.

The technology

Photothermal biomodulation

Blue light and controlled temperature (37 °C), applied to the patient’s own platelet-rich plasma inside the MCT Kit^®.

Light · 467 nm

Blue-light photobiomodulation

Blue light at 467 nm is applied under predefined exposure conditions as part of the Exosomes preset, which has been characterized for its ability to promote platelet-derived exosome release.

Temperature · 37 °C

Controlled temperature

The Exosomes preset uses a controlled temperature of 37 °C, maintaining near-physiological thermal conditions during PRP conditioning.

Inside the platelet

What happens inside the platelet

A step-by-step overview of how photothermal conditioning promotes platelet-derived extracellular vesicle release.

Photothermal conditioning

Blue light (467 nm) and controlled temperature (37 °C) are applied to the patient’s PRP inside the MCT Kit^®.

Platelet-derived exosome release

Photothermal conditioning promotes the release of exosomes from platelets.

The autologous approach

The patient’s own biology, at the point of care.

The Exosomes preset uses photothermal biomodulation to obtain autologous PRP enriched with platelet-derived exosomes and other extracellular vesicles.

SourceThe patient’s own blood
ProcessingPoint-of-care photothermal conditioning
Final preparationAutologous PRP enriched with platelet-derived extracellular vesicles
IsolationNo separate exosome isolation step required
EvidencePublished scientific and clinical research

Add-on for MCT Exosome protocols

Exo-Tech: Combining Plasma Gel and MCT Exosomes

Exo-Tech combines autologous plasma gel with PRP enriched with platelet-derived exosomes, creating an injectable autologous matrix.

The MCT System photothermally conditions the PRP, while the Exo-Tech Dry Bath prepares the plasma gel. Both components are obtained from the patient’s own blood.

Discover Exo-Tech

MCT R&D

Scientifically characterised

Platelet-derived extracellular vesicles characterised through nanoparticle tracking analysis (NTA), single-particle interferometric reflectance imaging sensing (SP-IRIS) and transmission electron microscopy (TEM).

109.2nm
Mean particle size · NTA

2.99× 10¹¹
Particles / mL · Mean NTA concentration

Platelet and EV-associated markers detected · SP-IRIS