MCT System · Preset

MCT Exosomes

Tailor-made secretomes via photothermal biomodulation.

Contact usHow it worksScientific evidence

Blue light
With controlled temperature

Enriched secretome
Extracellular vesicles & growth factors

Autologous
Exosomes at the point of care

What it does

The MCT System stimulates the release of autologous exosomes and extracellular vesicles for clinical use.

Beyond cell-based therapies, focused on clinical outcomes.

Growth factors

Photothermal biostimulation elicits controlled and sustained release of growth factors from platelets, achieving a more physiological effect.

Autologous exosomes

Cell and platelet photothermal conditioning stimulates exosome release, resulting in an enhanced regenerative product.

ATP synthesis

Photothermal biomodulation stimulates cellular metabolism and enhances ATP synthesis.

The technology

Photothermal biomodulation

Blue light and controlled temperature, applied to the patient’s own biological material inside the MCT Kit®.

Light · 467 nm

Exosomes and blue light

  • Blue light stimulus improves therapeutic effect.
  • Blue light exposure elevates miRNA levels and increases proangiogenic capabilities of MSCs.
  • Blue opsin photo-transduction is an invaluable tool for cell regenerative power enhancement.

Temperature · 37 °C

Exosomes and temperature

  • Temperature increases the frequency of exosome-cell membrane fusion events.
  • Exosome release kinetics are faster at higher temperatures.
  • Temperature reduces the number of tethered exosomes.

Inside the cell

What happens inside the cell

Photothermal biomodulation, step by step: from the light inside the MCT Kit® to the release of autologous exosomes.

01

Platelets and cells

Blue light and controlled temperature reach the patient’s own platelets and cells inside the MCT Kit®.

02

ATP synthesis

ATP is generated in the mitochondria.

03

Growth factors

Growth factors are released from the alpha granules.

04

Exosome release

Anchored multivesicular bodies (MVBs) release the exosomes.

Autologous vs non-autologous

MCT System delivers autologous exosomes, the natural and compatible messengers of your own body.

Autologous · MCT System

Medical level

  • SourceSame patient cells and tissues
  • CertificationCE / MDR
  • UseInjectable
  • ContentReliable
  • ResultsSignificant

Non-autologous

Cosmetic level

  • SourceAnimal, plants
  • CertificationCosmetic
  • UseTopical
  • ContentUncertain
  • ResultsUncertain

Add-on for MCT Exosome protocols

Exo-Tech: MCT Exosomes in a plasma gel scaffold

Exo-Tech turns the patient’s own plasma into an injectable scaffold that holds MCT Exosomes where they are needed.

The MCT System prepares the exosomes; the Exo-Tech Dry Bath builds the scaffold. One blood draw, fully autologous: no synthetic polymers, no foreign material.

Discover Exo-Tech

MCT R&D

Characterised in our lab

MCT Exosomes obtained from PRP, quantified by nanoparticle tracking analysis (NTA) and imaged by transmission electron microscopy (TEM).

109.2nm
Mean exosome size · NTA

299.3billion
Exosomes / mL per kit · NTA

Exosome protein markers confirmed · SP-IRIS

  • CD41a
  • CD63
  • CD81
  • CD9
0100200300400Size (nm)mean 109.2 nm
Size distribution · NTA. Representative sample of MCT Exosomes obtained from PRP.

Transmission electron microscopy image of an MCT Exosome, 69.00 nm Transmission electron microscopy image of an MCT Exosome, 82.35 nm Transmission electron microscopy image of an MCT Exosome, 53.40 nm Transmission electron microscopy image of an MCT Exosome, 31.37 nm

Transmission electron microscopy. Individual MCT Exosomes: spherical vesicles with a bilayer membrane, 31–82 nm.

MCT Academy

Published research on autologous exosomes

Scientific publications and case reports on exosomes from photothermally conditioned plasma, from bench to clinical practice.

All publicationsWatch the webinars

Autologous platelet-rich plasma exosome quantification after two thermo-photobiomodulation protocols with different fluences

Journal of Photochemistry and Photobiology · 2025 — Laura Cordero, Joan Carles Domingo, Elena Sánchez-Vizcaíno Mengual, Hernán Pinto

Regenerative Medicine

Human Blood Exosomes: Isolation and Characterization Methods, Variability, and the Need for Standardized Protocols—A Review

Biomedicines · 2025 — Elena Sánchez-Vizcaíno Mengual, Laura Cordero, Hernán Pinto

Regenerative Medicine

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