Orthopaedics & Sports Medicine

MCT System for PRP-derived exosomes

MCT System adds a one-touch photothermal conditioning step to your standard PRP, using controlled light and temperature to promote biological signalling before injection.

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CE Class IIa & IIb medical device · ISO 13485 · Point-of-care

For the MSK cases where

Standard PRP is not enough.

Not every patient responds to conventional PRP. Response varies with the patient and can be limited in complex, refractory cases.

Marín-Fermín et al., J ISAKOS 2024 · Boffa et al., Am J Sports Med 2024

Persistent pain

Limited function

Surgery not yet indicated

Need for rapid recovery

The evolution of PRP

Beyond platelets: PRP-derived exosomes

PRP, a platelet releasing extracellular vesicles, and one PRP-derived exosome magnified with its cargo: growth factors, proteins and microRNA
PRP, a platelet releasing extracellular vesicles, and one PRP-derived exosome magnified with its cargo: growth factors, proteins and microRNA

PRPPlateletExtracellular vesicles, including exosomesPRP-derived exosome

Beyond growth factors, PRP contains extracellular vesicles, including exosomes, involved in cell signalling, inflammation modulation and tissue remodelling.

MCT System amplifies the biological signal of PRP through controlled conditioning, promoting the release of platelet-derived extracellular vesicles.

  • Growth factors
  • Proteins
  • microRNA

What is MCT System?

Photothermal conditioning of autologous PRP.

MCT System applies controlled light and temperature to PRP to promote the release of extracellular vesicles and growth factors.

Inside the MCT System

  1. 01PRP conditioning
  2. 02Biological signalling
  3. 03PRP-derived exosome release
  4. The resultAutologous PRP enriched with platelet-derived exosomes
The MCT Unit with the drawer open and the MCT Kit inserted

Easy integration

One extra step. Same PRP workflow.

  1. Step 1Draw
  2. Step 2Prepare
  3. MCT SystemCondition · 10 minPhotothermal biomodulation
  4. Step 4InjectSame session

For acute & chronic MSK conditions

Amplifying the signal of autologous preparations

For musculoskeletal conditions

  • Grade II to IV OA
  • Chronic and acute tendinopathies
  • Ligament tears
  • Other MSK pathologies
MCT Unit touchscreen showing its three presets: PRP, Cells and Exosomes

AcuteMCT PlasmaChronicMCT Exosomes

Acute or chronic: the preset follows the clinical picture.

AcuteOn screen: PRP

MCT Plasma

Acute injuries & early-stage OA

Indications
  • Early-stage OA
  • Acute muscle, tendon and ligament injuries
  • Early tendinopathies
  • Sports soft-tissue injuries
  • Mild cartilage lesions

GoalEarly healing response

OutputEGF · bFGF · VEGFHigher growth factor levels than standard PRP1

Light620 nm · 1 J/cm² · 10 minTemperature4 °C · 15 min

1 Pinto H, Melamed G. PRIME Journal, 2020.

ChronicOn screen: EXOSOMES

MCT Exosomes

Chronic degenerative conditions

Indications
  • Moderate-to-advanced OA
  • Chronic tendinopathies
  • Degenerative tendon and ligament lesions
  • Recurrent and poor healing injuries
  • Degenerative cartilage lesions

GoalTissue homeostasis & remodelling

Output299.6 × 109particles / mL (NTA), in vitro2

Light467 nm · 1 J/cm² · 10 minTemperature37 °C · 10 min

2 Cordero L. et al. J Photochem Photobiol, 2025.

MCT in orthopaedics

Take PRP one step further.

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