AUTHORS
Aris Kaltsas, Dimitrios Hatzichristou
ABSTRACT
Introduction Erectile dysfunction and Peyronie’s disease are prevalent and frequently coexisting disorders in which guideline-based therapies improve symptoms more reliably than they reverse underlying corporal remodeling or tunical fibrosis. Regenerative biologics and nano-enabled delivery systems aim to intervene upstream in inflammatory and fibrotic pathways by improving local exposure, tissue persistence, and target engagement within the emerging field of regenerative sexual medicine. Objectives To synthesize current evidence on regenerative biologics and nano-enabled delivery platforms for erectile dysfunction and Peyronie’s disease, with emphasis on disease-specific delivery barriers, payload characterization, and translational readiness.
