Novel use of preconditioned autologous PRP-derived exosomes for partial Achilles tendon rupture repair: A three-week recovery case report

AUTHORS

Alberto Sánchez Herrera

ABSTRACT

Background Partial Achilles tendon ruptures are uncommon, often misdiagnosed, and lack effective regenerative treatments. Exosomes have emerged as a promising therapy to enhance tendon healing. Case report A 43-year-old male sustained a 5.5 mm partial Achilles tendon rupture during sports. He received autologous platelet-rich plasma (PRP)-derived exosomes using the MCT System (MCT kit plus MCT Unit). Fifteen milliliters of whole blood were centrifuged at 4000 rpm for 8 minutes to yield 10 mL PRP, which was placed in the MCT Kit and processed with the MCT Unit using the Exosome preset (1 J/cm 2 , 467 nm, 37 °C, 10 minutes) to prime platelets and stimulate exosome release.